The sermon centers on the eternal, unchanging holiness of God as revealed in Isaiah's vision of the throne room, where the seraphim cry 'Holy, holy, holy,' emphasizing God's infinite separation from sin and His sovereign, immutable nature. This divine holiness contrasts sharply with the fleeting, pride-filled reign of King Uzziah, whose disobedience and arrogance led to immediate judgment and lifelong exile, illustrating the fatal consequences of approaching God on one's own terms. The message underscores that a proper understanding of God's holiness leads to profound self-awareness and repentance, as seen in Isaiah's cry of 'Woe is me,' and similarly in Peter's reaction to Christ's glory, revealing that no sinner can stand in God's presence without mediation. The only way to approach this holy God is through Jesus Christ, the sinless High Priest who bore God's wrath in our place, making atonement possible and enabling sinners to be cleansed and reconciled. The sermon concludes with a call to humility, faith in Christ, and reliance on Scripture as the true source of revelation, affirming that God remains unchanged—holy, just, and merciful—inviting all to come to Him through the new and living way provided in Christ.