What does it mean to be confounded before God?

In Isaiah 45:16, being confounded refers to the ultimate dishonor faced by those who worship false gods. On the day of judgment, those who do not have Christ covering their sins will be publicly humiliated as their failures and guilt are laid bare. The seriousness of God's holiness and justice will mean that no excuse will stand, and there will be no refuge from eternal judgment. Understanding this clarifies the urgency for everyone to turn to the true God and place their faith in His Son for salvation.