Why is the rejection of Christ significant in the Bible?

The rejection of Christ by national Israel is significant as it fulfills the sovereign purpose of God that was established before the foundation of the world. According to Matthew 21, the parable of the wicked husbandmen illustrates that Israel was given the privilege of being God's chosen people, yet they rejected His messengers, culminating in the rejection of His Son. This rejection not only highlights humanity's sinful condition but also demonstrates that it is through God's sovereign plan that salvation is extended to the Gentiles.