How do we know that all humans are born in sin?

The universal doctrine of human depravity is clearly articulated in the Bible, particularly in passages like Romans 5:12, which indicates that sin entered the world through one man, Adam, and death through sin; thus, death spread to all men because all have sinned. This inherited sin nature denotes that every person is born in rebellion against God, characterized by a natural inclination towards self-interest and disobedience. Consequently, Scripture frequently emphasizes our need for a Savior to transform our hearts and bring us to reconciliation with God, illustrating the foundational principle of total depravity in Reformed theology.