What does the Bible say about the relationship between sin and our nature?

According to Scripture, particularly as outlined in Ephesians 2:1-3, all humans are born with a sinful nature, making them slaves to sin and subject to the desires of the flesh. This innate sinful condition affects every aspect of a person's being and cannot be remedied by human effort or will. Humans cannot change their nature; just as an Ethiopian cannot change his skin, they cannot choose righteousness over sin without divine intervention. It is only through God's sovereign grace, illustrated by Christ's redemptive work and the empowering of the Holy Spirit, that individuals are able to be transformed from being servants of sin to becoming servants of righteousness, thus illustrating the profound need for Christ as our Savior.