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How did man become lost according to the Bible?

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Man became lost through the sin of Adam, which brought death and separation from God to the entire human race.

The Bible clearly states that man became lost through the disobedience of Adam in the garden of Eden. Romans 5:12 explains that by one man's sin, death entered the world, affecting all humanity. In this representative way, Adam, as our federal head, fell into sin, and thus all his descendants are born into this state of lostness and separation from God. This loss is both imputed—counted against us as his descendants—and imparted through natural birth.
Scripture References: Genesis 3, Romans 5:12, Romans 5:18-19

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