How do we know that God commands respect for His chosen leaders?

In Numbers 12, we see a clear declaration from God regarding the special position of Moses. When Miriam and Aaron questioned Moses' authority, the Lord responded with a severe rebuke, highlighting that Moses had a unique relationship with Him, speaking to him 'mouth to mouth.' This indicates that disrespect toward God's appointed leaders is not taken lightly, and God views it as an offense against Himself. The teachings of Jesus also reaffirm that to speak against His bride, the church, is to act against Christ Himself, which underscores the importance of honoring those God has placed in leadership.