How do we know that sin has pernicious effects?

Sin's pernicious effects are convincingly depicted in Scripture, where it is described as deadly and destructive. For instance, in the narrative of Herod, we see that his rationalizations stem from a heart darkened by sin, leading to spiritual death (Romans 6:23). This is echoed in Psalm 2, which illustrates the futility of rebellion against God. The holistic biblical testimony underscores that sin distorts our understanding and consequently leads to rejection of God, resulting in grave consequences for humanity.