How do we know that the doctrine of Scripture is true?

The doctrine of Scripture is affirmed not only through its inspiration as mentioned in 2 Timothy 3:16, but also through its capacity to change lives. By examining the historical accuracy, fulfilled prophecy, and personal testimony of transformation in the lives of believers, we see evidence of its divine origin. 2 Peter 1:20-21 reminds us that prophecy came not from human will, but from holy men moved by the Holy Spirit, emphasizing that Scripture is authoritative and true. This collective evidence instills confidence in the reliability of God's Word.