What does it mean to be unregenerate?

To be unregenerate signifies a state of spiritual death, where an individual is alienated from God due to sin. Ephesians 2:1 states, "And you hath he quickened, who were dead in trespasses and sins." This condition is characterized by an inability to seek God or respond to spiritual truth without the regenerating work of the Holy Spirit. The process of regeneration is a divine act wherein God transforms the heart, enabling faith in Christ and the acceptance of the gospel. Until this transformation occurs, an unregenerate person remains in spiritual darkness, bound by sin and under the wrath of God.