What does the Bible say about calling upon God in times of trouble?

In times of distress, calling upon God is a central theme throughout the Scriptures. David exemplifies this in Psalm 55:16 when he states, 'As for me, I will call upon God, and the Lord shall save me.' This act of prayer reveals a deep reliance on God as the ultimate source of salvation and assistance during life's trials. The believer is encouraged to approach God with their sorrows and fears, trusting in His grace and power to intervene in their circumstances. In the same vein, Jesus invited the weary to come to Him for rest (Matthew 11:28), illustrating God's readiness to respond to those who seek Him earnestly.