What does the Bible say about God's appointments in life?

According to Hebrews 9:27-28, it is appointed unto men once to die, and after this comes judgment. This indicates that every event in our lives, not just significant events like death, is predetermined by God's sovereign will. Ecclesiastes 3:1 reinforces this by stating that there is a time for everything, an appointed occasion for every purpose under heaven. Isaiah 46:10 further elucidates this doctrine by explaining that God declares the end from the beginning, and everything that will come to pass has His divine appointment. Thus, in the Reformed tradition, we find comfort in the belief that nothing happens by chance; every occurrence is part of God's perfect plan.