What does the Bible say about human ignorance?

The Bible presents a stark view of human ignorance rooted in the fall of man. In Proverbs 30:2-3, Agur confesses his brutishness and lack of understanding, reflecting a broader biblical theme that humanity, created in God's image, has fallen into ignorance and sin. This ignorance is not just an absence of knowledge but a profound moral and spiritual blindness resulting from rebellion against God, as indicated in Genesis 3. The consequence of the fall is a darkened understanding, leading to a state where, as Jeremiah states, 'every man is brutish in his knowledge.' Without divine illumination, humanity cannot grasp the truth of God or the depths of their own condition.