What does the Bible say about ignorance of spiritual matters?

The Bible, particularly in 2 Peter 2:12, emphasizes the dangers of ignorance regarding spiritual truths. It describes those who speak evil of things they do not understand as 'natural brute beasts,' highlighting their pride and wickedness in condemning what they do not know. They may have some natural knowledge but lack the understanding necessary to grasp the nature of divine truths, leading them to corrupt themselves through their ignorance. This ignorance often manifests in the form of disdain for doctrines such as the dignity of angels and the proper government of church matters, which they ill-discern due to their lack of spiritual insight.