What does the Bible teach about the effects of sin?

Sin’s effects are pervasive and multifaceted, primarily introduced into the world through the fall of Adam and Eve. Romans 5:12 states, 'Wherefore, as by one man sin entered into the world, and death by sin; and so death passed upon all men, for that all have sinned.' This passage illuminates how sin has marred creation, causing not only spiritual death and separation from God but also physical afflictions such as sickness and death in the human body. The consequences of sin manifest in various forms throughout life, impacting relationships and the created order, thus reinforcing the need for salvation through Christ to restore what was lost.