What does the Bible teach about the nature of human sin?

Throughout the sermon, it is emphasized that all people, by nature, are at odds with God. As stated in Acts 4:26-27, even kings and rulers stand against the Lord and His anointed. This reflects the biblical teaching found in Ephesians 2:1-3, where it is revealed that we are dead in transgressions and sins, following the ways of the world. The human heart is deceitful (Jeremiah 17:9), inherently in rebellion against God's ways until transformed by His grace, demonstrating the necessity of a new heart through Jesus Christ.