The Bible teaches that unconverted men are spiritually dead in their sins, lacking the life of God and being unable to perform any acts acceptable to Him.
According to Ephesians 2:1, unconverted individuals are described as being dead in their trespasses and sins, emphasizing a total removal of spiritual life. This state of spiritual death parallels natural death, where a dead person cannot act or perceive; similarly, those dead in sin are utterly incapable of holy obedience unless quickened by the Holy Spirit. Just as a body devoid of the soul cannot function, a soul separated from God's grace is incapable of spiritual acts.
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