Because that, when they knew God, they glorified him not as God, neither were thankful; but became vain in their imaginations, and their foolish heart was darkened. - Romans 1:21
The context of this passage seems to deal primarily with the reprobation of those who give themselves up to homosexuality. However, the warrant of Almighty God is against all those who having the light of God’s creation, and the light of the Gospel, refused to reverence him in the knowledge he revealed to them. Therefore, he left them to themselves to do things which are not convenient, and without conscience. God gave them up to believe a lie, never to experience even the consideration of light again. Their foolish heart was darkened. Those whom God gives up are, and will forever be, deaf and blind to the living truth and life of the Gospel. They are untouched and unaffected by the preaching of the Gospel of Christ. They will never have a heart for the things of God and will continue to do as their foolish heart pleases to their own damnation.
It makes no difference what God says, they esteem themselves to be wiser than Him. They are unthankful and it is manifest by their irreverence, disrespect, disregard and rude attitude toward Him, his Word, and his church. Their refuge of lies will continually be reinforced. Their evil heart of unbelief will become more and more hardened and set in their own ways, which are the ways of death. There is a way which seemeth right unto a man, but the end thereof are the ways of death (Prv 14:12). This Biblical commentary of reprobation will never touch the heart of those whom God has given up. However, those to whom God has given the light of the knowledge of the glory of God in the face of Jesus Christ will flee to the throne of grace, that we may obtain mercy, and find grace to help in time of need. Those whom God has given up will one day soon hear him say, I never knew you: depart from me, ye that work iniquity.
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